Industry and academia are uniting to support the synthesis of quaric acid monomers as building blocks for drug discovery

Industry and academia are uniting to support the synthesis of quaric acid monomers as building blocks for drug discovery

Asynt, global visionaries in sustainable laboratory equipment, have collaborated with Kingston University (London, UK) and world-renowned chemical products supplier, Key Organics, to develop a new, accessible library of synthetic compounds.

Industry and academia are uniting to support the synthesis of quaric acid monomers as building blocks for drug discovery

Image credit: Ascent

Chemists from Wren’s group at Kingston University (UK) have formed a collaborative relationship with these industry leaders, enabling them to create a library of new synthetic compounds.

University chemists, Dr. Stephen P. Wren, Professor Adam Le Gresley, and doctoral candidate Nathan Long have constructed a preliminary synthetic compound library consisting of 28 quadratic anilino and benzyl amino monosaccharamide derivatives designed as biosimilars to the ubiquitous carboxylate. Acid ion.

They have been used to demonstrate the possibility of generating additional new compounds as compounds in this class can serve as substrates in further chemical transformations. Compounds can be provided in various forms to enrich drug discovery programs around the world.

By partnering with leading industry experts Asynt and Key Organics to unlock the potential of their ideas and enabling access to useful laboratory tools such as DrySyn oil-free heating blocks and CondenSyn waterless air concentrators as well as high-quality chemical feedstocks, the Wren Group are on a mission to advance new chemistry that can Accessible compounds that contain low-cost synthetic compounds are readily available for scientific research.

The Wren Group’s latest paper, published in SynOpen Theme Journal, outlines their work, and explains more about how DrySyn and CondenSyn can improve conditions and reaction success as well as reduce environmental impact in your laboratory. Read more on the pages of the magazine.

Dr. Ren explained that the partnership formed by the three organizations made the project possible. He goes on to explain this… “We chose to work alongside Asynt and Key Organics because they are leading suppliers of parallel synthesis equipment and chemical building blocks respectively. The Asynt equipment was easy to use and helped us maximize our production, while exchanging chemicals two-way with Key Organics was fun – I would like to thank them very much for their contribution.

Asynt is proud to be involved in this innovative work and is excited to see what’s next for Wren Group.

(tags for translation) drug discovery

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